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dc.contributor.authorLu, Chun-hua
dc.contributor.author鲁春华
dc.contributor.authorShen, Yue-mao
dc.contributor.author沈月毛
dc.contributor.authorZhao, Lin(Shandong Univ, Sch Life Sci, State Key Lab Microbial Technol)
dc.contributor.authorLi, Peng-fei(Shandong Univ, Sch Life Sci, State Key Lab Microbial Technol)
dc.contributor.authorLi, Shu-guang(Shandong Univ, Sch Life Sci, State Key Lab Microbial Technol)
dc.contributor.authorLi, Yue-zhong
dc.date.accessioned2011-06-20T08:23:15Z
dc.date.available2011-06-20T08:23:15Z
dc.date.issued2010
dc.identifier.citationThe Journal of Microbiology,Volume 48, Number 4, 438-444zh_CN
dc.identifier.issn1225-8873
dc.identifier.urihttp://dx.doi.org/doi:10.1007/s12275-010-0048-3
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/9673
dc.description.abstract3-O-alpha-D-ribofuranosyl epothilone A (epothiloneoside A) is a major component of glycosylated epothilones in Sorangium cellulosum strain So0157-2. The production and glycosylation ratios of epothiloneoside A in both solid and liquid culture conditions with various pH values and carbon sources were studied. The results showed that glycosylation occurs whenever epothilones are produced, regardless of changes in pH values, production time curves, and different carbon sources. We suggest that glycosylation is a stable process, paralleling the biosynthesis of epothilones in the So0157-2 strain.zh_CN
dc.description.sponsorshipNational Natural Science Foundation [30825001, 30671192]; 863 programs of China [2007AA02Z171, 2007AA021500]zh_CN
dc.language.isoenzh_CN
dc.publisherMICROBIOLOGICAL SOCIETY KOREAzh_CN
dc.subjectS. cellulosumzh_CN
dc.subjectepothiloneszh_CN
dc.subjectglycosylationzh_CN
dc.subjectepothiloneoside Azh_CN
dc.titleGlycosylation and Production Characteristics of Epothilones in Alkali-Tolerant Sorangium cellulosum Strain So0157-2zh_CN
dc.typeArticlezh_CN


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