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dc.contributor.advisor黄培强
dc.contributor.author刘文君
dc.date.accessioned2016-02-23T01:14:05Z
dc.date.available2016-02-23T01:14:05Z
dc.date.issued2015-05-18 16:17:19.0
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/96160
dc.description.abstract自然界中存在许多含吡咯环的生物碱,它们中大多都具有重要的生理活性,在医药生化等方面具有广阔的应用前景,而多羟基吡咯西里啶类生物碱由于其特殊的结构和生理药理性质,引起了人们的广泛的研究兴趣。本论文拓展了手性合成切块3,4-二羟基戊二酰亚胺的多用性,将其应用到骈环的吡咯西里啶类天然产物hyacinthacineA2和hyacinthacineA3的全合成中。一、HyacinthacineA2和HyacinthacineA3的不对称合成研究多羟基吡咯西里啶类生物碱广泛的存在于自然界中,并且对糖苷酶和糖苷转移酶有显著的抑制作用。近年,科学家们发现由麝香兰和野风信子分离得到的hyacinthacine类...
dc.description.abstractPyrrolizidine alkaloids occur widespread in nature and many of them possess a variety of important biological activities. Due to their interesting structural features and pharmacological properties, much effort has been directed towards the stereoselective synthesis of these natural products. In this dissertation, the D-O,O’-dibenzyltartaimide-based synthetic methodology, developed from our labora...
dc.language.isozh_CN
dc.relation.urihttps://catalog.xmu.edu.cn/opac/openlink.php?strText=46178&doctype=ALL&strSearchType=callno
dc.source.urihttps://etd.xmu.edu.cn/detail.asp?serial=20836
dc.subject不对称合成
dc.subjectHyacinthacine
dc.subject还原烷基化
dc.subject还原-环化
dc.subjectWacker氧化
dc.subjectCytosporone B
dc.subjectAsymmetric synthesis
dc.subjectHyacinthacine
dc.subjectReductive alkylation
dc.subjectReductive-cyclization
dc.subjectWacker’s Oxidation
dc.subjectCytosporone B
dc.title天然产物Hyacinthacine A2 和HyacinthacineA3 的不对称合成研究
dc.title.alternativeStudies on Asymmetric Synthesis of Hyacinthacine A2 and Hyacinthacine A3
dc.typethesis
dc.date.replied2008-12-04
dc.description.note学位:理学硕士
dc.description.note院系专业:化学化工学院化学系_有机化学
dc.description.note学号:20520061151936


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