Show simple item record

dc.contributor.authorHuang, Pei-Qiang
dc.contributor.author黄培强
dc.contributor.authorChen, Guo
dc.contributor.authorZheng, Xiao
dc.date.accessioned2011-06-15T01:22:41Z
dc.date.available2011-06-15T01:22:41Z
dc.date.issued2009-03
dc.identifier.citationJOURNAL OF HETEROCYCLIC CHEMISTRY,2007,44(2):499-501zh_CN
dc.identifier.issn0022-152X
dc.identifier.urihttp://dx.doi.org/doi:10.1002/jhet.5570440239
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/9511
dc.description.abstractFrom the known lactone (S)-4, easily derived from L-glutamic acid, a scalable approach to chiral building block O-silylated 3-hydroxypiperidin-2-one 3 and alkaloid 1 was achieved in five and six-steps respectively. The key steps are a chemoselective amidation of lactone-ester 5 and a one-pot reductive borane-decomplexation, N-debenzylation and cyclization.zh_CN
dc.language.isoenzh_CN
dc.publisherHETERO CORPORATIONzh_CN
dc.titleA new synthesis of alkaloid (S)-3-hydroxypiperidin-2-one and its O-TBS protected derivativezh_CN
dc.typeArticlezh_CN


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record