Show simple item record

dc.contributor.authorLi, Weitaozh_CN
dc.contributor.authorSun, Xiaolianzh_CN
dc.contributor.authorWang, Yuzh_CN
dc.contributor.authorNiu, Gangzh_CN
dc.contributor.authorChen, Xiaoyuanzh_CN
dc.contributor.authorQian, Zhiyuzh_CN
dc.contributor.authorNie, Liminzh_CN
dc.contributor.author王瑜zh_CN
dc.contributor.author陈小元zh_CN
dc.date.accessioned2015-07-22T07:37:30Z
dc.date.available2015-07-22T07:37:30Z
dc.date.issued2014 August 1zh_CN
dc.identifier.citationBiomedical Optics Express, 2014,5(8):2679-2685zh_CN
dc.identifier.other20143118001864zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/93728
dc.description.abstractWe developed a high-resolution photoacoustic microscopy (PAM) system with a near-infrared (NIR) laser to noninvasively monitor the distribution of gold nanostar (GNS) in blood vessels, liver and spleen in mice. Photoacoustic images of organs at deep depths were continuously acquired in vivo every 30 minutes after a single dose of GNS by tail vein injection. The experimental results showed that GNS accumulated significantly in both liver and spleen from blood circulation after administration, which was qualitatively validated by fluorescence imaging. Our studies demonstrate that PAM might be potentially used for noninvasive tracing the kinetics of exogenous nanoparticles in biological system. ? 2014 Optical Society of America.zh_CN
dc.language.isoen_USzh_CN
dc.publisherOptical Society of American (OSA)zh_CN
dc.source.urihttp://dx.doi.org/10.1364/BOE.5.002679zh_CN
dc.subjectBlood vesselszh_CN
dc.subjectInfrared deviceszh_CN
dc.subjectMammalszh_CN
dc.subjectPhotoacoustic microscopyzh_CN
dc.titleIn vivo quantitative photoacoustic microscopy of gold nanostar kinetics in mouse organszh_CN
dc.typeArticlezh_CN


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record