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dc.contributor.authorLiu, Jingzh_CN
dc.contributor.authorLiu, Dong-Yingzh_CN
dc.contributor.authorChen, Wenzh_CN
dc.contributor.authorLi, Jin-Linzh_CN
dc.contributor.authorLuo, Fanzh_CN
dc.contributor.authorLi, Qingzh_CN
dc.contributor.authorLing, Jia-Xinzh_CN
dc.contributor.authorLiu, Yuan-Yuanzh_CN
dc.contributor.authorXiong, Hai-Rongzh_CN
dc.contributor.authorDing, Xiao-Huazh_CN
dc.contributor.authorHou, Weizh_CN
dc.contributor.authorZhang, Yunzh_CN
dc.contributor.authorLi, Shi-Yuezh_CN
dc.contributor.authorWang, Jiezh_CN
dc.contributor.authorYang, Zhan-Qiuzh_CN
dc.contributor.author李晴zh_CN
dc.date.accessioned2015-07-22T07:36:23Z
dc.date.available2015-07-22T07:36:23Z
dc.date.issued2012-02zh_CN
dc.identifier.citationVIRUS RESEARCH, 2012,163(2):439-447zh_CN
dc.identifier.otherWOS:000301309400004zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/93118
dc.descriptionNational High Technology Research and Development 863 Program of China [2007AA02Z465]; National Natural Science Foundation of China (NSFC) [30770096]; National Natural Science Foundation of Jiangsu province [BK2010537]; State Key Laboratory of Virology [2010006]; Scientific Research Foundation of the State Education Ministry for Returned Chinese Scholars [30115]; Fundamental Research Funds for the Central Universities [3082003]zh_CN
dc.description.abstractHantaan virus (HTNV) and Seoul virus (SEOV) are two major zoonotic pathogens of hemorrhagic fever with renal syndrome (HFRS) in Asia. Hubei province, which is located in the central-south China, had been one of the most severe epidemic areas of HFRS. To investigate phylogenetic relationships, genetic diversity and geographic distribution of HTNV and SEOV in their reservoir hosts, a total of 687 rodents were trapped in this area between 2000 and 2009. Sequences of partial S- and M-segments of hantaviruses and mitochondrial D-loop gene from 30 positive samples were determined. Our data indicated that SEOV and HTNV were co-circulating in Hubei. Phylogenetic analysis based on partial S- and M-segment sequences revealed two and three previously undefined lineages of SEOV, and a novel genetic lineage of HTNV, respectively. Four inter-lineage reassortment SEOVs carried by Rattus norvegicus and Apodemus agrarius were observed. It suggests that SEOV may cause spillover infections to A. agrarius naturally. The abundance of the phylogenetic lineages of SEOV suggested that central-south China was a radiation center for SEOVs. Crown Copyright (C) 2011 Published by Elsevier B.V. All rights reserved.zh_CN
dc.language.isoen_USzh_CN
dc.publisherVIRUS RESzh_CN
dc.source.urihttp://dx.doi.org/10.1016/j.virusres.2011.11.006zh_CN
dc.subjectEPIDEMIC HEMORRHAGIC-FEVERzh_CN
dc.subjectREPUBLIC-OF-CHINAzh_CN
dc.subjectRENAL SYNDROMEzh_CN
dc.subjectHANTAAN VIRUSzh_CN
dc.subjectNUCLEOCAPSID PROTEINzh_CN
dc.subjectPUUMALA HANTAVIRUSzh_CN
dc.subjectHUBEI PROVINCEzh_CN
dc.subjectSEOUL VIRUSzh_CN
dc.subjectDIVERSITYzh_CN
dc.subjectEVOLUTIONzh_CN
dc.titleGenetic analysis of hantaviruses and their rodent hosts in central-south Chinazh_CN
dc.typeArticlezh_CN


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