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dc.contributor.authorZhong, Qizh_CN
dc.contributor.authorZeng, Wenhuazh_CN
dc.contributor.authorHuang, Xiaoyangzh_CN
dc.contributor.authorWang, Boliangzh_CN
dc.contributor.authorCai, Mingzh_CN
dc.contributor.author曾文华zh_CN
dc.contributor.author黄晓阳zh_CN
dc.contributor.author王博亮zh_CN
dc.contributor.author蔡明zh_CN
dc.date.accessioned2015-07-22T07:10:37Z
dc.date.available2015-07-22T07:10:37Z
dc.date.issued2014 Augustzh_CN
dc.identifier.citationJournal of Mechanics in Medicine and Biology, 2014,14(4)zh_CN
dc.identifier.issn0219-5194zh_CN
dc.identifier.other20142917941411zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/90401
dc.description.abstractObjectives: To investigate the influences caused by special morphologies and dynamics of the substructures of mitral valve by the explicit finite element program LS-DYNA. Methods: A new finite element model for the mitral apparatus characterized by layered structure of leaflets tissue, saddle shape and contraction of annulus, an approximately accurate morphology of chordae tendineae was developed. The coaptation length, leaflets stress and strain of the present model were compared with those of two auxiliary models, one with planar annulus and the other with fixed annulus. The tensile function and force distribution of chordae tendineae were analyzed in the models with and without chordae tendineae. Results: The stretch ratios computed by the present model were most closely to the experimental data. The leaflets instantly turned over to the atrial side and larger load was observed in the model without chordae tendineae. Besides, tensile force was highly correlated with average diameter of chordae tendineae (r = 0.965). Conclusion: The saddle shape of annulus benefits valve coaptation and the contraction of annulus could help decrease loads on leaflets and prevent stress concentrating excessively. Chordae tendineae could bear partial loads on the leaflets, and prevent the leaflets to turn over to the side of the atrium and help the valve close successfully. ? 2014 World Scientific Publishing Company.zh_CN
dc.language.isoen_USzh_CN
dc.publisherWORLD SCIENTIFIC PUBL CO PTE LTDzh_CN
dc.source.urihttp://dx.doi.org/10.1142/S0219519414500572zh_CN
dc.subjectBiomechanicszh_CN
dc.subjectMorphologyzh_CN
dc.subjectTissuezh_CN
dc.titleFinite element modeling of the human mitral valve: Implications of morphologies and dynamics of the annulus and the chordae tendineaezh_CN
dc.typeArticlezh_CN


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