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dc.contributor.authorBull, Steven D.zh_CN
dc.contributor.authorDavidson, Matthew G.zh_CN
dc.contributor.authorVan den Elsen, Jean M. H.zh_CN
dc.contributor.authorFossey, John S.zh_CN
dc.contributor.authorJenkins, A. Toby A.zh_CN
dc.contributor.authorJiang, Yun-Baozh_CN
dc.contributor.authorKubo, Yujizh_CN
dc.contributor.authorMarken, Frankzh_CN
dc.contributor.authorSakurai, Kazuozh_CN
dc.contributor.authorZhao, Jianzhangzh_CN
dc.contributor.authorJames, Tony D.zh_CN
dc.contributor.author江云宝zh_CN
dc.date.accessioned2015-07-22T03:20:08Z
dc.date.available2015-07-22T03:20:08Z
dc.date.issued2013-Feb 19zh_CN
dc.identifier.citationACCOUNTS OF CHEMICAL RESEARCH, 2013,46(2):312-326zh_CN
dc.identifier.otherWOS:000315478700012zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/88653
dc.descriptionEPSRC; Royal Society; Leverhulme Trust; Japan Society for the Promotion of Science (JSPS); GB Sasakawa Foundation; Daiwa Foundation; University of Birmingham; University of Bathzh_CN
dc.description.abstractBoronic acids can interact with Lewis bases to generate boronate anions, and they can also bind with diol units to form cyclic boronate esters. Boronic acid based receptor designs originated when Lorand and Edwards used the pH drop observed upon the addition of saccharides to boronic acids to determine their association constants. The inherent acidity of the boronic acid is enhanced when 1,2-, 1,3-, or 1,4-diols react with boronic acids to form cyclic boronic esters (5, 6, or 7 membered rings) in aqueous media, and these interactions form the cornerstone of diol-based receptors used in the construction of sensors and separation systems. In addition, the recognition of saccharides through boronic acid complex (or boronic ester) formation often relies on an interaction between a Lewis acidic boronic acid and a Lewis base (proximal tertiary amine or anion). These properties of boronic acids have led to them being exploited in sensing and separation systems for anions (Lewis bases) and saccharides (diols). The fast and stable bond formation between boronic acids and diols to form boronate esters can serve as the basis for forming reversible molecular assemblies. In spite of the stability of the boronate esters' covalent B-O bonds, their formation is reversible under certain conditions or under the action of certain external stimuli. The reversibility of boronate ester formation and Lewis acid-base interactions has also resulted in the development and use of boronic acids within multicomponent systems. The dynamic covalent functionality of boronic acids with structure-directing potential has led researchers to develop a variety of self-organizing systems including macrocycles, cages, capsules, and polymers. This Account gives an overview of research published about boronic acids over the last 5 years. We hope that this Account will inspire others to continue the work on boronic acids and reversible covalent chemistry.zh_CN
dc.language.isoen_USzh_CN
dc.publisherAMER CHEMICAL SOCzh_CN
dc.source.urihttp://dx.doi.org/10.1021/ar300130wzh_CN
dc.subjectFLUORESCENCE TRANSDUCTIONzh_CN
dc.subjectSACCHARIDE DETECTIONzh_CN
dc.subjectENANTIOMERIC PURITYzh_CN
dc.subjectSIMPLE PROTOCOLSzh_CN
dc.subjectNMR ANALYSISzh_CN
dc.subjectSENSORSzh_CN
dc.subjectESTERIFICATIONzh_CN
dc.subjectCHEMOSENSORSzh_CN
dc.subjectELECTROPHORESISzh_CN
dc.subjectSTRATEGYzh_CN
dc.titleExploiting the Reversible Covalent Bonding of Boronic Acids: Recognition, Sensing, and Assemblyzh_CN
dc.typeArticlezh_CN


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