A concise approach to (+)-1-epi-castanospermine
Abstract
A concise enantioselective synthesis of (+)-1-epi-castanospermine (2) is described, which featured the use of chiral non-racemic tetramic acid derivative 5 as a synthetic equivalent of the challenging synthon A through a highly diastereoselective vinylogous Mukaiyama type reaction. (C) 2007 Elsevier Ltd. All rights reserved.