Synthesis, Characterizations, and Crystal Structures of -Hydroxyphosphonic Acid Esters

Abstract

This article describes the synthesis of -hydroxyphosphonic acid esters using the Pudovik reaction. IR, 1H NMR, 13C NMR, 31P NMR, MS, and elemental analysis were employed to confirm their structures. X-ray structure analysis is reported for six compounds. The antibacterial activities of these compounds are also reported. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.