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dc.contributor.author温兰玲zh_CN
dc.contributor.author李娜zh_CN
dc.contributor.author钱洪流zh_CN
dc.date.accessioned2011-04-26T08:24:09Z
dc.date.available2011-04-26T08:24:09Z
dc.date.issued2008-04zh_CN
dc.identifier.citation中国实验诊断学 中国实验诊断学 ,2008,12(4):469-470zh_CN
dc.identifier.issn1007-4287zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/8508
dc.description.abstract目的观察米非司酮对滋养叶细胞P-糖蛋白(p-glycoprotein P-gp)表达的影响方法应用免疫组织化学方法,对30例药物流产的绒毛组织进行P-gp染色,取30例人工流产的绒毛组织作为对照。结果人工流产标本中的绒毛上皮的P-gp表达全部呈强阳性。而药物流产的绒毛90%表(P<0.01)达呈弱阳性。结论米非司酮抑制P-gp的表达提示该药可能将作为化疗增效剂试用于临床。 【英文摘要】 Objective To observe the influence of mifepristone on expression of P-gp in trophoblastic cells.Methods Immunohistochemical method was used to detect the expression of p-glycoprotein (P-gp) in chorion obtained from 30 cases of artificial abortion by taking mifepristone,another 30 cases of artificial abortion with aspiration were detected as controls.Results All the trophoblastic cells of chorion from aspiration expressed a stronger staining of p-gp,whereas the expression of P-gp in 90% of those with mifepri...zh_CN
dc.language.isozhzh_CN
dc.publisher吉林大学中日联谊医院、上海第二医科大学附属瑞金医院zh_CN
dc.subjectP-糖蛋白zh_CN
dc.subject米非司酮zh_CN
dc.subjectp-glycoproteinzh_CN
dc.subjectmifepristonezh_CN
dc.title米非司酮对滋养叶细胞p-糖蛋白表达的影响zh_CN
dc.title.alternativeThe influence of mifepristone on expression of P-gp in trophoblastic cellszh_CN
dc.typeArticlezh_CN


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