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dc.contributor.advisor杭纬
dc.contributor.author黄真真
dc.date.accessioned2016-01-14T02:48:46Z
dc.date.available2016-01-14T02:48:46Z
dc.date.issued2014-02-26 09:49:32.0
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/77002
dc.description.abstract膀胱癌是全球泌尿生殖系统发病率最高的癌症,每年有超过350,000新发病例。大约70%的膀胱癌患者在被确诊时还处于癌症早期,此时肿瘤多为膀胱内粘膜浅表的乳头状瘤,转移风险低,手术根治后可以获得较长的生存时间。侵犯膀胱壁肌层的非乳头状瘤转移风险高,预后较差;肾癌每年大约有208,000新发病例,其发病率在泌尿生殖系统所有癌症中排名第二,是致死率最高的癌症。当肾癌肿瘤局限于肾脏器官或者周围组织时,手术治疗的存活率可以达到70%。不幸的是,大约50%的肾癌患者在被确诊时已经处于肾癌晚期或者发生全身性转移,即便接受治疗,患者的5年存活率也不足2%。因此,早期诊断方法,尤其是非侵入式的诊断方法对提高膀胱...
dc.description.abstractBladder cancer (BC) is the most common genitourinary malignancy. Each year, over 350, 000 new cases were diagnosed worldwide. Approximately 70% BC patients can acquire long-term survival, associated with superficial papillary lesions limited to the mucosa and submucosa of the bladder. Nonpapillary tumor that invades the bladder wall always has a high propensity for metastasis, and the prognosis is...
dc.language.isozh_CN
dc.relation.urihttps://catalog.xmu.edu.cn/opac/openlink.php?strText=40110&doctype=ALL&strSearchType=callno
dc.source.urihttps://etd.xmu.edu.cn/detail.asp?serial=40460
dc.subject代谢组学
dc.subject多肽组学
dc.subject液相色谱-质谱
dc.subject标志物
dc.subject膀胱癌
dc.subject肾癌
dc.subjectMetabonomics
dc.subjectPeptidomics
dc.subjectLC-MS
dc.subjectBiomarker
dc.subjectBladder cancer
dc.subjectKidney cancer
dc.title基于液质联用技术的膀胱癌肾癌尿液代谢组学及血清多肽组学研究
dc.title.alternativeLC-MS Based Urine Metabonomics and Serum Peptidomics on Bladder and Kidney Cancers
dc.typethesis
dc.date.replied2013-06-07
dc.description.note学位:理学博士
dc.description.note院系专业:化学化工学院_分析化学
dc.description.note学号:20520100153632


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