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dc.contributor.authorCai,HRzh_CN
dc.contributor.authorZeng,Wzh_CN
dc.contributor.authorZheng,ZHzh_CN
dc.contributor.authorSu,WJzh_CN
dc.contributor.authorLi,Jzh_CN
dc.contributor.authorYang,ZYzh_CN
dc.contributor.authorHuang,YJzh_CN
dc.contributor.author黄耀坚zh_CN
dc.date.accessioned2013-12-12T02:24:51Z
dc.date.available2013-12-12T02:24:51Z
dc.date.issued2000-07-01zh_CN
dc.identifier.citationFems Microbiology Letters, 2000,188(1):87-91zh_CN
dc.identifier.issn0378-1097zh_CN
dc.identifier.otherWOS:000087931600015zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/65965
dc.description.abstractThe purpose of this work was to screen the actinomycetes having antitumor or antimicrobial activity, which were isolated from the surface, epidermis and intestines of sea plants and animals collected from the Taiwan Strait, China. Antitumor activity was studied by the MTT assay and DNA target activity was studied by the biochemical induction assay while antimicrobial activity was determined by observing bacterial and fungal growth inhibition. 20.6% of marine actinomycete cultures displayed cytotoxic activity on P388 cells at dilutions at and below 1:320 and 18.6% on KB cells. 2.96% of marine actinomycete cultures displayed inducing activity. Among all marine actinomycetes isolated, the genus Micromonospora has the highest positive rate of inducing activity. However, most antimicrobial activity was found in the genus Streptomyces. These results indicate that marine organism associated actinomycetes could be a promising source for antitumor and antimicrobial bioactive agents. (C) 2000 Published by Elsevier Science B.V. on behalf of the Federation of European Microbiological Societies.zh_CN
dc.language.isoen_USzh_CN
dc.source.urihttp://dx.doi.org/10.1111/j.1574-6968.2000.tb09173.xzh_CN
dc.subjectMETABOLITESzh_CN
dc.subjectBACTERIAzh_CN
dc.subjectASSAYzh_CN
dc.titleDetection of antitumor and antimicrobial activities in marine organism associated actinomycetes isolated from the Taiwan Strait, Chinazh_CN
dc.typeArticlezh_CN


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