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dc.contributor.authorHan, J. H.zh_CN
dc.contributor.authorMolkentin, J. D.zh_CN
dc.contributor.author韩家淮zh_CN
dc.date.accessioned2013-12-12T02:24:45Z
dc.date.available2013-12-12T02:24:45Z
dc.date.issued2000zh_CN
dc.identifier.citationTrends in Cardiovascular Medicine,10(1):19-22zh_CN
dc.identifier.issn1050-1738zh_CN
dc.identifier.otherISI:000166162600004zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/65860
dc.description.abstractMyocyte enhancer factor-2 (MEF2), transcription factors and mitogen-activated protein kinase (MAPK) p38 are regulators of cardiac development and various pathophysiologic processes. The recent finding that p38 can directly regulate MEF2 transcription factors suggests a novel mechanism for reprogramming cardiac gene expression in response to neuroendocrine and/or stress stimulation. This review weighs the accumulating evidence for a p38 MAPK-MEF2 signal transduction cascade and discusses ifs role in cardiac myocyte biology. (Trends Cardiovasc Med 2000; 10:19-22). (C) 2000 Elsevier Science Inc.zh_CN
dc.language.isoen_USzh_CN
dc.subjectACTIVATED PROTEIN-KINASESzh_CN
dc.subjectTRANSCRIPTION FACTOR MEF2Czh_CN
dc.subjectN-TERMINAL KINASESzh_CN
dc.subjectGENE-EXPRESSIONzh_CN
dc.subjectCARDIAC-HYPERTROPHYzh_CN
dc.subjectMUSCLE DIFFERENTIATIONzh_CN
dc.subjectSERUM INDUCTIONzh_CN
dc.subjectPATHWAYzh_CN
dc.subjectSTRESSzh_CN
dc.subjectAPOPTOSISzh_CN
dc.titleRegulation of MEF2 by p38 MAPK and its implication in cardiomyocyte biologyzh_CN
dc.typeArticlezh_CN


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