Show simple item record

dc.contributor.authorAkihiro Sakaizh_CN
dc.contributor.authorJiahuai Hanzh_CN
dc.contributor.authorAndrew CB Catozh_CN
dc.contributor.authorShizuo Akirazh_CN
dc.contributor.authorJianDong Lizh_CN
dc.contributor.author韩家淮zh_CN
dc.date.accessioned2013-12-12T02:24:40Z
dc.date.available2013-12-12T02:24:40Z
dc.date.issued2004zh_CN
dc.identifier.citationBmc Molecular Biology,5zh_CN
dc.identifier.issn1471-2199zh_CN
dc.identifier.otherISI:000221696200001zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/65749
dc.description.abstractBackground: Despite the importance of glucocorticoids in suppressing immune and inflammatory responses, their role in enhancing host immune and defense response against invading bacteria is poorly understood. Toll-like receptor 2 (TLR2) has recently gained importance as one of the major host defense receptors. The increased expression of TLR2 in response to bacteria-induced cytokines has been thought to be crucial for the accelerated immune response and resensitization of epithelial cells to invading pathogens.zh_CN
dc.language.isoen_USzh_CN
dc.subjectNONTYPABLE HAEMOPHILUS-INFLUENZAEzh_CN
dc.subjectTOLL-LIKE RECEPTOR-2zh_CN
dc.subjectNF-KAPPA-Bzh_CN
dc.subjectMUC5AC MUCIN TRANSCRIPTIONzh_CN
dc.subjectSIGNAL-TRANSDUCTIONzh_CN
dc.subjectENDOTHELIAL-CELLSzh_CN
dc.subjectIMMUNE FUNCTIONzh_CN
dc.subjectHOST-DEFENSEzh_CN
dc.subjectIN-VIVOzh_CN
dc.subjectPATHWAYzh_CN
dc.titleGlucocorticoids synergize with IL-1 beta to induce TLR2 expression via MAP kinase phosphatase-1-dependent dual inhibition of MAPK JNK and p38 in epithelial cellszh_CN
dc.typeArticlezh_CN


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record