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dc.contributor.authorShi, J. J.zh_CN
dc.contributor.authorMa, X. H.zh_CN
dc.contributor.authorDiao, H. L.zh_CN
dc.contributor.authorNi, H.zh_CN
dc.contributor.authorXu, L. B.zh_CN
dc.contributor.authorZhu, H.zh_CN
dc.contributor.authorYang, Z. M.zh_CN
dc.contributor.author杨增明zh_CN
dc.date.accessioned2013-12-12T02:24:08Z
dc.date.available2013-12-12T02:24:08Z
dc.date.issued2005zh_CN
dc.identifier.citationHistology and Histopathology,20(4):1021-1028zh_CN
dc.identifier.issn0213-3911zh_CN
dc.identifier.otherISI:000232715000002zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/65208
dc.description.abstractPGE2 is essential for mammalian female reproduction. This study was to examine the expression of EP2 gene in the rat uterus during early pregnancy, delayed implantation and artificial decidualization by in situ hybridization and immunohistochemistry. There was no detectable EP2 mRNA expression in the uterus from days I to 4 of pregnancy (day 1 = day of vaginal sperm). A low level of EP2 immunostaining was observed in the luminal and glandular epithelium from days 1 to 4 of pregnancy. Both EP2 mRNA and protein expression were highly detected in the luminal epithelium at implantation sites on day 6 of pregnancy. EP2 expression decreased from day 7 of pregnancy and was undetectable on days 8 and 9 of pregnancy. After delayed implantation was terminated by estrogen treatment and the embryo implanted, both EP2 mRNA and protein expression were strongly observed in the luminal epithelium at the implantation site. There was no detectable EP2 expression in both control and decidualized uteri. In conclusion, these data suggest that EP2 expression at implantation site may play an important role during embryo implantation in rats.zh_CN
dc.language.isoen_USzh_CN
dc.subjectprostaglandinzh_CN
dc.subjectEP2zh_CN
dc.subjectratzh_CN
dc.subjectuteruszh_CN
dc.subjectpregnancyzh_CN
dc.titleDifferential expression of prostaglandin E receptor subtype EP2 in rat uterus during early pregnancyzh_CN
dc.typeArticlezh_CN


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