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dc.contributor.authorShao, Yizh_CN
dc.contributor.authorQuyang, Luowazh_CN
dc.contributor.authorZhou, Yuepingzh_CN
dc.contributor.authorTang, Jingzh_CN
dc.contributor.authorTan, Yuehuizh_CN
dc.contributor.authorLiu, Qiupingzh_CN
dc.contributor.authorLin, Zhirongzh_CN
dc.contributor.authorYin, Tingtingzh_CN
dc.contributor.authorQiu, Fangfangzh_CN
dc.contributor.authorLiu, Zuguozh_CN
dc.contributor.author汤儆zh_CN
dc.date.accessioned2013-12-12T02:13:04Z
dc.date.available2013-12-12T02:13:04Z
dc.date.issued2010-07zh_CN
dc.identifier.citationIn Vitro Cellular & Developmental Biology-Animal, 2010,46(7):600-605zh_CN
dc.identifier.issn1071-2690zh_CN
dc.identifier.otherISI:000279657100006zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/62669
dc.descriptionNational High Technology Research and Development Program of the Eleventh Five-Year Plan of China [2006AA02A131]; National Natural Science Fundation of China [30600697, 30572001, 30700926]zh_CN
dc.description.abstractThis study was to investigate the stability, physico-mechanical property and biocompatibility of porcine corneal acellularized matrix (PCAM) that was prepared using human sera treatment to decellularize corneas. The stability (the rate of biodegradation) and physico-mechanical property (water uptake, density, and porosity) of PCAM were not compromised, compared with porcine fresh cornea matrix (PFCM, p > 0.05). The contact and extract cytotoxicity tests with human corneal epithelial cells and human keratocytes showed that PCAM has a good biocompatibility ex vivo and no cytotoxic effect. These results present the ability to create safety scaffolds that function as cornea grafts and provide a novel experimental approach for the study of cornea tissue engineering using acellular porcine cornea.zh_CN
dc.language.isoen_USzh_CN
dc.source.urihttp://dx.doi.org/10.1007/s11626-010-9328-9zh_CN
dc.subjectCROSS-LINKED COLLAGENzh_CN
dc.subjectXENOTRANSPLANTATIONzh_CN
dc.subjectEQUIVALENTzh_CN
dc.subjectSCAFFOLDzh_CN
dc.subjectPROGRESSzh_CN
dc.subjectBABOONSzh_CN
dc.subjectSTROMAzh_CN
dc.subjectRABBITzh_CN
dc.titlePreparation and physical properties of a novel biocompatible porcine corneal acellularized matrixzh_CN
dc.typeArticlezh_CN


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