Inorganic Nanoparticles for Biomedical Applications
Tan, Mei Chee
Chow, Gan Moog
- 材料学院－已发表论文 
Polymer, lipid, metal, semiconductor, and hybrid composite nanoparticles with dimensions < 100 nm, have been developed extensively for potential biomedical applications like drug delivery systems, molecular sensing devices, and diagnostic imaging. In this overview, only inorganic nanoparticles for drug delivery will be addressed. Inorganic nanoparticles exhibit magnetic, electrical and optical properties that differed from their bulk counterparts. These physical properties could be tailored by controlling the size, shape, surface, and domain interactions in the nanoparticles. The incorporation of the unique properties of nanoparticles has expanded alternative platforms for drug delivery. The drug delivery systems highlighted in this overview include unguided, magnetically-guided, and optically-triggered delivery systems. These delivery systems are developed to enable improved localization and control of the drug’s sphere of influence. This would potentially allow for more efficient therapy with lower dosages and reduced adverse side effects.