Superhydrophilic/Superhydrophobic Surface Constructions on Titanium and Their Effects on Anti-bacterial Properties
- 2011年第17卷 
生物材料植入人体后若受到细菌感染就可能导致植入手术失败，因此植入材料的抗菌性研究具有重要的意义。由于内植物感染的第一步是细菌在材料表面的贴附，植入材料的表面性质对其抗菌性有决定性的影响。本文通过电化学法在钛表面构筑一层超亲水或超疏水的表面膜层，并运用体外抗菌性试验来研究材料表面的润湿性对细菌贴附的影响，以期利用改变材料表面的润湿性达到抗菌作用。结果表明，相比超亲水表面，超疏水表面上贴附的细菌数明显减少。The microbial infection of biomaterials often causes clinic problems and sometimes even leads to the prosthesis failure. It is, therefore, important to prevent the biomaterials from bacterial contamination. This can be done by using anti-bacteria drugs. However, this method causes physiological burdens to the patients and does not always work. To stop the contamination from the just beginning is believed to be a better choice. The first step for infection is the attachment of bacteria on the material. In this work, the thin TiO2 nanotubes array films were constructed with totally different wettabilities showing either superhydrophobic or superhydrophilic. The bacterial attachment behaviors on them were evaluated. It is shown that the numbers of viable colonies on the superhydrophobic film were significantly less than those on the superhydrophilic one.