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dc.contributor.author程红芬zh_CN
dc.contributor.author张勇zh_CN
dc.contributor.author刘杰zh_CN
dc.contributor.author刘艳梅zh_CN
dc.contributor.authorCHENG Hong-fenzh_CN
dc.contributor.authorZHang Yongzh_CN
dc.contributor.authorLIU Jiezh_CN
dc.contributor.authorLIU Yan-meizh_CN
dc.date.accessioned2013-11-18T07:46:50Z
dc.date.available2013-11-18T07:46:50Z
dc.date.issued2009-08-28zh_CN
dc.identifier.citation电化学,2009,15(03):326-330.zh_CN
dc.identifier.issn1006-3471zh_CN
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/58249
dc.description.abstract应用线性扫描伏安法和循环伏安法研究盐酸柔红霉素在银盘电极上的电化学行为及其与牛血清白蛋白(BSA)的相互作用.结果表明,在pH6.50的Britton-Robinson缓冲溶液中,盐酸柔红霉素有一灵敏的还原峰,峰电位Ep-0.64V(vs.SCE),缓冲液加入BSA后盐酸柔红霉素的还原峰峰电流下降,据此建立了BSA的电化学测定方法.在优化条件下,峰电流与BSA浓度于1.0×10-8~1.0×10-4mol·L-1(r=0.9965)范围内呈线性关系,检出限为5.0×10-9mol·L-1.同时还测定了盐酸柔红霉素与BSA的结合比和结合常数.zh_CN
dc.description.abstractThis article used the linear sweep voltammetry and the circulation voltammetry to study the electrochemical behavior of daunorubicin hydrochloride on galactic disk electrode and its electrode reaction with BSA.Also it studied the interaction of daunorubicin hydrochloride with BSA.The results showed that daunorubicin hydrochloride has a sensitive reduction peak at -0.64 V(vs. SCE) in pH 6.50 Britton-Robinson buffer.The valus of reductions peak current reduced by the addition of BSA to the above mentioned solution.A new electrochemical determination method of bovine serum albumin was developed based on the interaction of daunorubicin hydrochloride with BSA.Furthermore,under the optimized condition,the decrease of the reduction peak current of daunorubicin hydrochloride is proportional to the concentration of BSA in the range of 5.0×10-8 mol·L-1~1.0×10-4 mol·L-1(r=0.9965).The limit of detection is 5.0×10-9 mol·L-1.The binding ratio and binding constant of daunorubicin hydrochloride with BSA were calculated.zh_CN
dc.language.isozhzh_CN
dc.publisher厦门大学《电化学》编辑部zh_CN
dc.relation.ispartofseries研究论文zh_CN
dc.relation.ispartofseriesArticleszh_CN
dc.source.urihttp://electrochem.xmu.edu.cn/CN/abstract/abstract8511.shtmlzh_CN
dc.subject盐酸柔红霉素zh_CN
dc.subject银盘电极zh_CN
dc.subject电化学行为zh_CN
dc.subject牛血清白蛋白(BSA)zh_CN
dc.subjectdaunorubicin hydrochloridezh_CN
dc.subjectgalactic disk electrodezh_CN
dc.subjectelectrochemical behaviorzh_CN
dc.subjectbovine serum albumin(BSA)zh_CN
dc.title银盘电极盐酸柔红霉素电化学行为及其与BSA的相互作用zh_CN
dc.title.alternativeThe Electrochemical Behavior of Daunorubicin Hydrochloride on Galactic Disk Electrode and its Reaction with BSAzh_CN
dc.typeArticlezh_CN
dc.description.note作者联系地址:山西大学化学化工学院;zh_CN
dc.description.noteAuthor's Address: School of Chemistry and Chemical Engineering,Shanxi University,Taiyuan 030006,Chinazh_CN


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