具有双模态造影作用的碘剂-羧甲基壳聚糖磁性纳米颗粒的制备与检测
The preparation and detection of N-carboxymethyl chitosan coated iron oxide magnetic nanoparticles loaded with iodine for MR/CT dual-imaging
Abstract
电子计算机体层成像技术(ComputedTomography,CT)是一种非常重要的非侵袭性的医学诊断技术,目前广泛应用于临床诊断过程中。其对于胃肠道、肝脏、心血管和骨的成像以及对于肿瘤成像效果较好,对比非常明显。但这种成像技术也存在一些缺点,如CT对脑部组织和软组织(如肌肉、肌腱等)及软骨等组织的分辨率较低,不利于诊断这些部位的疾病。而另一种成像技术,磁共振成像(MagneticResonanceImaging,MRI)同样是目前广泛应用的非侵袭性的医学诊断技术。在MRI成像中,获得的软组织成像分辨率高,利于诊断,但MRI的设备昂贵,检查费用较高,常规扫描时间较长,这些缺点极大地限制了其发展... Computed tomography (CT) is a non-invasive medical diagnostic technology, which is widely used in diagnostic process. It shows clearer imaging about the gastrointestinal, liver, cardiovascular, bone and tumor. But this technology also has some disadvangtages such as low resolution on brain tissue,soft tissue (muscles, tendons),the cartilage and other tissue. Magnetic resonance imaging (MRI) is als...