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dc.contributor.advisor金鑫
dc.contributor.author景佐
dc.date.accessioned2018-12-05T01:49:52Z
dc.date.available2018-12-05T01:49:52Z
dc.date.issued2018-04-12
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/170882
dc.description.abstract研究背景: 动脉粥样硬化(Atherosclerosis,AS)的病理发展进程是一种慢性炎症反应,且是内皮损伤后的一系列进行性疾病。油酰乙醇胺(Oleoylethanolamide,OEA)是一种存在于组织和循环血液的内源性脂肪酸乙醇胺类化合物。已有大量文献报道,OEA具有降低脂质代谢,调节饮食、降低体重、神经保护及延长寿命等多种生物学作用。但是OEA抗动脉粥样硬化的作用及机制尚未可知。本论文分别通过体内体外实验,探究了OEA对血管损伤后新生内膜的形成及由血小板衍生生长因子(Plateletderivedgrowthfactor,PDGF)诱导的大鼠原代主动脉平滑肌细胞(RatVascula...
dc.description.abstractBackground: The pathogenesis of atherosclerosis (AS) is a chronic inflammatory response and is a series of progressive diseases after endothelial injury. Oleoylethanolamide (OEA) is an endogenous fatty acid ethanolamine compound present in tissue and circulating blood. OEA has a variety of biological effects such as lowering lipid metabolism, regulating diet, reducing body weight, neuroprotection ...
dc.language.isozh_CN
dc.relation.urihttps://catalog.xmu.edu.cn/opac/openlink.php?strText=60377&doctype=ALL&strSearchType=callno
dc.source.urihttps://etd.xmu.edu.cn/detail.asp?serial=62029
dc.subject油酰乙醇胺
dc.subjectAMPK
dc.subjectrVSMCs
dc.subjectOleoylethanolamide
dc.subjectAMPK
dc.subjectrVSMCs
dc.title油酰乙醇胺改善大鼠球囊损伤后新生内膜的形成
dc.title.alternativeEffect of Oleoylethanolamide on neointimal formation after balloon injury in rats
dc.typethesis
dc.date.replied2017-05-17
dc.description.note学位:医学硕士
dc.description.note院系专业:医学院_药理学
dc.description.note学号:24520141153590


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