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dc.contributor.advisor王守森
dc.contributor.advisor魏梁锋
dc.contributor.author张灏
dc.date.accessioned2018-12-05T01:49:50Z
dc.date.available2018-12-05T01:49:50Z
dc.date.issued2018-04-12
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/170870
dc.description.abstract中文摘要 第一部分:创伤性脑损伤合并海水淹溺大鼠脑水肿的时程变化研究 目的通过检测创伤性脑损伤(traumaticbraininjury,TBI)合并海水淹溺大鼠伤后不同时间点的脑组织水、Na+和K+含量及血脑屏障(bloodbrainbarrier,BBB)通透性,探究此类复合伤伤后脑水肿的时程变化。 方法216只SD大鼠随机分为正常对照组(N组,n=6)、假手术组(A组,n=14)、单纯脑损伤组(B组,n=98)、脑损伤合并海水淹溺组(C组,n=98)。Marmarou法颅脑致伤(450g×1.5m)+气管内泵入海水(3ml/kg)建立创伤性脑损伤合并海水淹溺大鼠模型。采用干湿重法测...
dc.description.abstractAbstract Part Ⅰ The Study on the Changes of Brain Edema after Trauma Brain Injury Accompanied by Seawater Drowning in Rats Objectives: To observe the change of brain edema in traumatic brain injury (TBI) rats with seawater drowning by detecting the brain water,Na+,K+ content and the permeability of blood brain barrier(BBB). Methods:Totally 216 male rats were randomly divided into normal contro...
dc.language.isozh_CN
dc.relation.urihttps://catalog.xmu.edu.cn/opac/openlink.php?strText=60319&doctype=ALL&strSearchType=callno
dc.source.urihttps://etd.xmu.edu.cn/detail.asp?serial=62683
dc.subject创伤性脑损伤
dc.subject创伤性脑水肿
dc.subject海水淹溺
dc.subject急性肺损伤
dc.subjectAQP4
dc.subject氨甲酰化促红细胞生成素
dc.subject治疗
dc.subject神经保护作用
dc.subject大鼠
dc.subject动物模型
dc.subjectTraumatic brain injury
dc.subjectTraumatic brain edema
dc.subjectSeawater drowning
dc.subjectAcute lung injury
dc.subjectAQP4
dc.subjectErythropoietin
dc.subjectCarbamylated erythropoietin
dc.subjectNeuroprotective
dc.subjectRats
dc.subjectAnimal model
dc.title创伤性脑损伤合并海水淹溺大鼠脑水肿变化及C-EPO的干预作用研究
dc.title.alternativeExperimental Research on Brain Edema and Beneficial Effect of C-Erythropoietin in Traumatic Brain Injury Rats with Seawater Drowning
dc.typethesis
dc.date.replied2017-05-19
dc.description.note学位:医学硕士
dc.description.note院系专业:医学院_外科学
dc.description.note学号:24520141153551


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