| dc.contributor.advisor | 王团老 | |
| dc.contributor.author | 张家明 | |
| dc.date.accessioned | 2018-12-05T01:48:59Z | |
| dc.date.available | 2018-12-05T01:48:59Z | |
| dc.date.issued | 2018-04-09 | |
| dc.identifier.uri | https://dspace.xmu.edu.cn/handle/2288/170780 | |
| dc.description.abstract | Rab蛋白属于Ras超家族，是其中最大的一个家族。在哺乳动物细胞中已经发现70种以上的Rab蛋白。Rab蛋白通过结合GTP或GDP的转换来发挥其分子开关的作用，进而调控细胞囊泡的形成、靶向、黏附和融合，在细胞内蛋白质运输过程中扮演非常重要的角色，Rab功能异常与很多疾病的发生密切相关。Rab39是一种新发现的Rab蛋白，Rab39有两个成员：Rab39a和Rab39b。人类Rab39a基因定位于常染色体11q22.3上，而Rab39b基因定位于性染色体Xq28上。不管是对于Rab39a亦或是Rab39b，关于它们的研究都甚少。 本文通过对Rab39的定位研究发现，Rab39a和Rab39b都... | |
| dc.description.abstract | Rab protein belongs to the Ras superfamily and is one of the largest family. More than 70 Rab proteins have been found in mammalian cells. Rab protein plays a very important role in the process of intracellular protein transport by regulating the formation, targeting, adhesion and fusion of cell vesicles by combining the effects of GTP or GDP conversion, The disease is closely related. Rab39 is a ... | |
| dc.language.iso | zh_CN | |
| dc.relation.uri | https://catalog.xmu.edu.cn/opac/openlink.php?strText=59903&doctype=ALL&strSearchType=callno | |
| dc.source.uri | https://etd.xmu.edu.cn/detail.asp?serial=62235 | |
| dc.subject | Rab39 | |
| dc.subject | RILP | |
| dc.subject | 自噬 | |
| dc.subject | Rab39 | |
| dc.subject | RILP | |
| dc.subject | autophagy | |
| dc.title | Rab39对细胞自噬影响的研究 | |
| dc.title.alternative | Effect of Rab39 on Autophagy | |
| dc.type | thesis | |
| dc.date.replied | 2017-05-08 | |
| dc.description.note | 学位：理学硕士 | |
| dc.description.note | 院系专业：药学院_化学生物学 | |
| dc.description.note | 学号：32320141153402 | |
