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dc.contributor.advisor夏宁邵
dc.contributor.advisor程通
dc.contributor.author巫洋涛
dc.date.accessioned2018-12-05T01:37:35Z
dc.date.available2018-12-05T01:37:35Z
dc.date.issued2018-04-09
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/169906
dc.description.abstract手足口病(HFMD)和水痘是主要影响婴儿和儿童的两种主要急性传染病,每年导致大量的发病人数,给儿童的健康带来严重威胁。HFMD的主要发病人群为6个月至5岁的儿童,自2008年HFMD在我国大陆地区大爆发以来,每年的发病人数平均都在200万以上。引起HFMD的病原体是以EV71和CA16为主的肠道病毒,尤其EV71是引起重症HFMD神经并发症和死亡的最主要病原体。除HFMD外,水痘是另一种非常普遍的儿童急性传染病,主要出现在小于14岁的儿童。引起水痘的唯一病原体是水痘-带状疱疹病毒(VZV),该病毒在全球也流行非常广泛,超过90%的人呈血清阳性。目前,虽然HFMD和水痘都有相应的疫苗上市,但每年...
dc.description.abstractHand-foot-mouth disease (HFMD) and chickenpox are two major acute infectious diseases that mainly affect infants and children, causing significant morbidity annually and posing a serious threat to children's health. Since 2008, HFMD outbreak in China mainland, the average annual incidence of more than 2 million, and affect mainly 6 months to 5 years old children. Two major etiological agents that ...
dc.language.isozh_CN
dc.relation.urihttps://catalog.xmu.edu.cn/opac/openlink.php?strText=59946&doctype=ALL&strSearchType=callno
dc.source.urihttps://etd.xmu.edu.cn/detail.asp?serial=62533
dc.subject肠道病毒71型
dc.subject水痘-带状疱疹病毒
dc.subject联合疫苗
dc.subjectEnterovirus 71
dc.subjectVaricella-Zoster Virus
dc.subjectCombined vaccine
dc.title肠道病毒71型与水痘-带状疱疹病毒联合表位疫苗研究
dc.title.alternativeA novel combined vaccine based on monochimeric VLP co-displaying conserved epitopes against Enterovirus 71 and Varicella-Zoster Virus
dc.typethesis
dc.date.replied2017-05-20
dc.description.note学位:理学硕士
dc.description.note院系专业:生命科学学院_生物化学与分子生物学
dc.description.note学号:21620141152568


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