短小芽孢杆菌类群（Bacillus pumilus group）分类、泛基因组学与环境适应性研究

Abstract

短小芽孢杆菌类群（Bacilluspumilusgroup，简称Bpgroup）是芽孢杆菌属中短小芽孢杆菌（B.pumilus）与其近缘种的统称，此类群菌株可合成多种活性物质，在工农医等领域具有重要的应用价值。此类群菌株种间16SrRNA相似度达99.5%，许多数据库的菌株因使用16SrRNA基因分类被错误命名，因此，准确定种有必要开展高精度系统进化研究；目前已有研究大多针对陆地环境分离的菌株，对海洋来源Bpgroup多菌株的基因组学研究未见报道，其基因组学研究相对滞后。本研究对本实验室分离的17株Bpgroup菌株（16株分离自海洋，1株分离自土壤）进行了基因组测序，并对52株Bpgroup...

Bacillus pumilus group (Bp group) strains have been studied due to their agronomic, industrial or pharmaceutical potential in synthesizing enzymes, antibiotics and other active products. However, classifying of strains in this taxonomic group at species level is a big challenge since it is composed of four species that share among them over 99.5% of 16S rRNA gene identity, thus requiring high reso...