半夏泻心汤治疗慢性胃炎随机平行对照研究

Abstract

[目的]观察半夏泻心汤治疗慢性胃炎疗效。[方法]使用随机平行对照方法,将74例住院及门诊患者按掷骰子法简单随机分为两组。对照组37例奥美拉唑,20mg/次,2次/d;多潘立酮,10mg/次,3次/d。治疗组37例半夏泻心汤(黄连、干姜各3g,大枣、甘草、黄芩、半夏各6g,党参10g;食欲下降加紫苏叶10g,焦三仙15g;恶心呕吐加代赭石15g,旋复花10g;腹痛加白芍20g,乌药、延胡索各10g;腹胀加佛手、陈皮、木香各10g;泛酸加吴茱萸3g,海螵蛸10g,瓦楞子煅20g),1剂/d,水煎400m L,早晚口服,200m L/次;西药治疗同对照组。连续治疗60d为1疗程。观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈21例,显效9例,有效5例,无效2例,总有效率94.59%。对照组痊愈13例,显效10例,有效6例,无效8例,总有效率78.38%。治疗组疗效优于对照组(P<0.05)。[结论]半夏泻心汤治疗慢性胃炎疗效满意,无严重不良反应,值得推广。

[Objective]To observe Banxiaxiexin Tang efficacy of the treatment of chronic gastritis.[Methods]randomized,parallel controlled method,74 inpatients and outpatients by dice method is simple randomized into two groups.Omeprazole 37 cases in the control group,20mg/times,2 times/d;domperidone,10mg/time,3 times/d.The treatment group 37 cases Banxiaxiexin Tang(Huanglian,Ganjiang 3g,Dazao,Gancao,Huangqin,Banxia 6g,Dangshen 10g;appetite add Zisuye 10 g,Jiaosanxian 15g;nausea and vomiting plus Daizheshi 15 g,Xuanfuhua 10g;abdominal pain plus Baishao 20 g,Wuyao,Yanhusuo each 10g;bloating plus Foushou,Chenpi,Muxiang each 10g;pantothenic acid plus Wuzhuyu 3g,Haipiaoxiao 10 g,Walengzi 20g),1 ji/d,water fried 400 m L,sooner or later,oral,200 m L/second;western medicine with the control group.60 d for a course of continuous treatment.Observation of clinical symptoms,adverse reactions.One course of treatment,to determine efficacy.[Results]The cure 21 cases,effective in 9 cases,effective in 5 cases,2 cases,the total efficiency of 94.59%.Cured 13 cases in the control group,10 cases markedly effective in 6 cases,8 cases,the total efficiency of 78.38%.Treatment group than the control group(P<0.05).[Conclusion]Banxiaxiexin Tang treatment of chronic gastritis results were satisfactory,no serious adverse reactions,is worth promoting.