细胞凋亡与自噬在心血管疾病中的作用研究

Abstract

细胞凋亡与自噬是普遍存在于各种细胞内的生命现象,广泛参与了机体的生理、病理过程,且二者有着多因子、多通路的相互影响,这种错综复杂的关系贯穿于各种心血管疾病的始终,对多种心血管疾病的发生发展转归起重要作用。现对细胞凋亡与自噬及其相互关系进行梳理,并综述其在心血管疾病中的作用。

Apoptosis and autophagy are common life phenomenon in various cells, which widely involve in physiological and pathological processes, and interact with one another by many factors and multiple pathways. This intricate relationship runs through a variety of cardiovascular diseases, and plays an important role in the occurrence, development and prognosis of many cardiovascular diseases. The effects of apoptosis and autophagy and their interrelationship in cardiovascular diseases were reviewed and summarized in this paper.