Analysis of Influence Factors of Nasal Endoscopy in Treatment of Chronic Rhinosinusitis with Nasal Polypsis
- 医学院－已发表论文 
目的探讨鼻内镜治疗慢性鼻-鼻窦炎的临床疗效及其影响因素。方法方便选择该院2010年1月—2015年1月收治的慢性鼻-鼻窦炎患者93例行鼻内镜手术。分别于术前、术后6个月、12个月对VAS及Lund-Kennedy评分进行统计分析评估疗效。对影响手术疗效的因素进行分析。结果鼻内镜术后6、12个月,头面部胀痛感、鼻塞、鼻分泌物和鼻后滴漏等症状明显改善,VAS评分术后6个月与术前比较,术后12个月与术后6个月比较,差异均有统计学意义(P<0.05);Lund-Kennedy评分在术前、术后6个月及12个月分别为(13.61±2.26)分、(6.32±2.29)分和(4.57±2.79)分,各时间点比较均差异有统计学意义(P<0.05);多因素Logistic回归分析结果显示,是否伴息肉、多鼻窦发病、鼻窦手术后复发、有无变应性鼻炎病史、是否长期应用鼻减充血剂及鼻内镜术后是否坚持综合治疗均会对慢性鼻-鼻窦炎手术疗效产生影响,是其独立影响因素。结论鼻内镜治疗慢性鼻-鼻窦炎可有效改善患者的临床症状。影响其术后疗效的因素较多。Objective To explore the influence factors of nasal endoscopy in treatment of chronic rhinosinusitis with nasal polypsis(CRN P). Methods Convenient selection from January 2010 to January 2015, 93 cases with CRNP from our hospital were selected. The curative effect was evaluated at pre-operation, postoperative 6 and 12 months by comparing the VAS and Lund-Kennedy score. The influence factors were selected and analyzed. Results The symptoms of rhinobyon, nasal discharge, postnasal drip and distending pain of head and face showed marked improvement at postoperative 6 months and postoperative 12 months. There were significant differences in VAS score about postoperative 6 months and pre-operation,and the comparative result in VAS score about postoperative 12 months and postoperative 6 months(P<0.05). In pre-operation, postoperative 6 months and postoperative 12 months, the Lund-Kennedy score was(13.61 ±2.26)points,( 6.32 ±2.29)points and(4.57 ±2.79)points, there was a significant difference among groups(P <0.05). Multivariable logistic analysis showed that whether or not with polyp, attack of multisinusitis, sinus recurred after operation, if they used nasal decongestant preparation long time, if it had allergic rhinitis and whether keep comprehensive treatment. All of them were the influence factors in treatment of CRNP. Conclusion Treatment of CRNP can effectively improve patient's clinical symptoms, and there were many influencing factors.