Now showing items 1-3 of 3

    • Brd4 and JMJD6-Associated Anti-Pause Enhancers in Regulation of Transcriptional Pause Release 

      Wen Liu; 刘文; Qi Ma; Kaki Wong; Wenbo Li; Kenny Ohgi; Jie Zhang; Aneel K. Aggarwal; Michael G. Rosenfeld (Cell Press, 2013-12-19)
      Distal enhancers characterized by the H3K4me mark play critical roles in developm ental and transcriptional programs. However, potential roles of specific distal regulatory elements in regulating RNA polymerase II (Pol II) ...
    • JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex 

      Wei-wei Gao; Rong-quan Xiao; Wen-juan Zhang; Yi-ren Hu; Bing-ling Peng; Wen-juan Li; Yao-hui He; Hai-feng Shen; Jian-cheng Ding; Qi-xuan Huang; Tian-yi Ye; Ying Li; Zhi-ying Liu; Rong Ding; Michael G.Rosenfeld; Wen Liu; 刘文 (Elsevier Inc., 2018-04)
      【Abstract】Whereas the actions of enhancers in gene transcriptional regulation are well established, roles of JmjC-domain-containing proteins in mediating enhancer activation remain poorly understood. Here, we report that ...
    • Methylation of transcription factor YY2 regulates its transcriptional activity and cell proliferation 

      Xiao-nan Wu; 吴晓男; Tao-tao Shi; 石涛涛; Yao-hui He; 何耀辉; Fei-fei Wang; 王绯绯; Rui Sang; Jian-cheng Ding; Wen-juan Zhang; Xing-yi Shu; Hai-feng Shen; Jia Yi; Xiang Gao; Wen Liu; 刘文 (Macmillan Publishers Limited,part of Springer Nature, 2017-10)
      【Abstract 】Yin Yang 1(YY1) is a multifunctional DNA-binding transcription factor shown to be critical in a variety of biological processes, and its activity and function have been shown to be regulated by multitude of ...