Now showing items 1-2 of 2

    • Celastrol-induced Nur77 interaction with TRAF2 alleviates inflammation by promoting mitochondrial ubiquitination and autophagy 

      Mengjie Hu; 胡梦婕; Qiang Luo; 罗强; Gulimiran Alitongbieke; 古丽米然·阿里同别克; Shuyi Chong; Chenting Xu; Lei Xie; Xiaohui Chen; Duo Zhang; Yuqi Zhou; Zhaokai Wang; Xiaohong Ye; Lijun Cai; Fang Zhang; Huibin Chen; Fuquan Jiang; Hui Fang; Shanjun Yang; Jie Liu; Maria T.Diaz-Meco; Ying Su; Hu Zhou; Jorge Moscat; Xiangzhi Lin; 林祥志; Xiao-kun Zhang; 张晓坤 (Elsevier Inc., 2017-04)
      【Abstract】Mitochondria play an integral role in cell death, autophagy, immunity and inflammation. We previously showed that Nur77, an orphan nuclear receptor, induces apoptosis by targeting mitochondria. Here, we report ...
    • Modulation of nongenomic activation of PI3K signaling by tetramerization of N-terminally-cleaved RXRα 

      Liqun Chen; 陈鲤群; Alexander E.Aleshin; Gulimiran Alitongbieke; Yuqi Zhou; Xindao Zhang; Xiaohong Ye; Mengjie Hu; Gaoang Ren; Ziwen Chen; Yue Ma; Duo Zhang; Shuai Liu; Weiwei Gao; Lijun Ca; Lingjuan Wu; Zhiping Zeng; Fuquan Jiang; Jie Liu; Hu Zhou; Gregory Cadwell; Robert C.Liddington; Ying Su; 苏迎; Xiao-kun Zhang; 张晓坤 (Macmillan Publishers Limited,part of Springer Nature, 2017-07)
      【Abstract】Retinoid X receptor-alpha (RXRa) binds to DNA either as homodimers or heterodimers, but it also forms homotetramers whose function is poorly defined. We previously discovered that an N-terminally-cleaved form of ...