Synthesis of Acrylonitriles through an FeCl3-Catalyzed Domino Propargylic Substitution/Aza-Meyer-Schuster Rearrangement Sequence
Date
2012-05Author
Hao, Lu
Wu, Feng
Ding, Zong-Cang
Xu, Su-Xia
Ma, Yan-Li
Chen, Li
Zhan, Zhuang-Ping
詹庄平
Collections
- 化学化工-已发表论文 [14237]
Abstract
Nontoxic cyanide source: An unprecedented route to acrylonitriles by employing propargylic alcohols and para-tolylsulfonohydrazide as a combined cyano source has been developed (see scheme). This efficient and practical cyanation reaction proceeds through an FeCl3-catalyzed domino propargylic substitution/aza-Meyer–Schuster rearrangement sequence, the rearrangement process of which is reported for the first time.
Citation
CHEMISTRY-A EUROPEAN JOURNAL,2012,18(21):6453-6456URI
http://dx.doi.org/10.1002/chem.201200763WOS:000304045000008
https://dspace.xmu.edu.cn/handle/2288/15509