| dc.contributor.author | Dai Xijie | |
| dc.contributor.author | Huang Peiqiang | |
| dc.contributor.author | 黄培强 | |
| dc.date.accessioned | 2013-01-24T01:20:06Z | |
| dc.date.available | 2013-01-24T01:20:06Z | |
| dc.date.issued | 2012-09 | |
| dc.identifier.citation | CHINESE JOURNAL OF CHEMISTRY，2012,30（9）：1953-1956 | zh_CN |
| dc.identifier.issn | 1001-604X | |
| dc.identifier.uri | http://dx.doi.org/10.1002/cjoc.201200660 | |
| dc.identifier.uri | WOS:000309400700006 | |
| dc.identifier.uri | https://dspace.xmu.edu.cn/handle/2288/14672 | |
| dc.description.abstract | A novel strategy was developed for a rapid access to the naturally occurring racemic neoclausenamide and its analogs, which featured a highly erythro-selective vinylogous Mukaiyama type reaction (dr=12:1) and a highly diastereoselective tandem conjugate addition-Davis oxidation of N-Boc-pyrrol-2(5H)-one 5 (dr=10:1). Remarkably, the skeleton of neoclausenamide, namely 8a, an analog of neoclausenamide, was built in just two steps with all the four stereogenic centers (relative stereochemistry) established correctly and in excellent diastereoselectivities. | zh_CN |
| dc.description.sponsorship | National Basic Research Program (973 Program) of China [2010CB833200]; NSF of China [20832005, 20902075] | zh_CN |
| dc.language.iso | en | zh_CN |
| dc.publisher | WILEY-V C H VERLAG GMBH | zh_CN |
| dc.subject | ( plus /-)-neoclausenamide | zh_CN |
| dc.subject | vinylogous Mukaiyama reaction | zh_CN |
| dc.subject | tandem reaction | zh_CN |
| dc.subject | stereoselective synthesis | zh_CN |
| dc.subject | pyrrol-2(5H)-one | zh_CN |
| dc.title | A Short and Flexible Synthetic Approach to the Naturally Occurring Racemic Neoclausenamide and Its Analogs | zh_CN |
| dc.type | Article | zh_CN |
