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Molecular and cellular mechanisms for Alzheimer‘s disease: Understanding APP metabolism
Alzheimer's disease (AD) is the most common neurodegenerative disease associated with aging. One important pathologic feature of AD is the formation of extracellular senile plaques in the brain, whose major components are ...
APP processing in Alzheimer's disease
An important pathological feature of Alzheimer's disease (AD) is the presence of extracellular senile plaques in the brain. Senile plaques are composed of aggregations of small peptides called beta-amyloid (A beta). Multiple ...