Browsing 生物医学－已发表论文 by Author "Yao, Xinsheng"
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A novel screening model for the molecular drug for diabetes and obesity based on tyrosine phosphatase Shp2 (vol 21, pg 874, 2011)
Bu, Yanyan; Shi, Tao; Meng, Minghui; Kong, Guiping; Tian, Yingpu; Chen, Quancheng; Yao, Xinsheng; Feng, Gensheng; Chen, Haifeng; Lu, Zhongxian; 吕忠显 (2011-03-15) -
A resveratrol analog, phoyunbene B, induces G2/M cell cycle arrest and apoptosis in HepG2 liver cancer cells
Wang, Guanghui; Guo, Xiaoyu; Chen, Haifeng; Lin, Ting; Xu, Yang; Chen, Quancheng; Liu, Jie; Zeng, Jinzhang; Zhang, Xiao-kun; Yao, Xinsheng; 陈海峰 (2012-03-01)Among the seven natural resveratrol analogs separated and identified from Pholidota yunnanensis R-OLFE, we found phoyunbene B (PYB, trans-3,4'-dihydroxy-2',3',5-trimethoxystilbene) was more effective in inhibiting the ... -
Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2
Liu, Dongping; Kong, Guiping; Chen, Quan Cheng; Wang, Guanghui; Li, Jie; Xu, Yang; Lin, Ting; Tian, Yingpu; Zhang, Xiaokun; Yao, Xinsheng; Feng, Gensheng; Lu, Zhongxian; Chen, Haifeng; 吕忠显 (2011-11-15)Src homology-2 domain-containing protein tyrosine phosphatase (Shp2), a novel proto-oncogenic protein, is an important target in cancer therapy research. Approximately 2000 plant extracts were screened to find its natural ... -
Total synthesis and RXR alpha-mediated transcription studies of neriifolone B and related compounds
Shen, Qirong; Dai, Yi; Wang, Guanghui; Yao, Fei; Duan, Yinghui; Chen, Haifeng; Zhang, Weige; Zhang, Xiaokun; Yao, Xinsheng; 王光辉 (PERGAMON-ELSEVIER SCIENCE LTD, 2014-05-01)Neriifolone B (1), a natural product containing a novel 4',4'-dimethyl-4',5'-dihydropyran-6-one[2',3':3,4]xanthone skeleton, was found to be a potent inhibitor of transcription mediated by retinoid X receptor alpha (RXR ...