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    • Alzheimer's beta-Secretase (BACE1) Regulates the cAMP/PKA/CREB Pathway Independently of beta-Amyloid 

      Chen, Yaomin; Huang, Xiumei; Zhang, Yun-wu; 张云武; Rockenstein, Edward; Bu, Guojun; Golde, Todd E.; Masliah, Eliezer; Xu, Huaxi; 许华曦 (SOC NEUROSCIENCE, 2012-08-15)
      beta-Amyloid protein (A beta), the major component of neuritic plaques in Alzheimer's disease (AD), is derived from proteolytic cleavages of the amyloid precursor protein (APP) by beta-site APP-cleaving enzyme 1 (BACE1) ...