Now showing items 1-2 of 2

    • Alzheimer's beta-Secretase (BACE1) Regulates the cAMP/PKA/CREB Pathway Independently of beta-Amyloid 

      Chen, Yaomin; Huang, Xiumei; Zhang, Yun-wu; 张云武; Rockenstein, Edward; Bu, Guojun; Golde, Todd E.; Masliah, Eliezer; Xu, Huaxi; 许华曦 (SOC NEUROSCIENCE, 2012-08-15)
      beta-Amyloid protein (A beta), the major component of neuritic plaques in Alzheimer's disease (AD), is derived from proteolytic cleavages of the amyloid precursor protein (APP) by beta-site APP-cleaving enzyme 1 (BACE1) ...
    • Appoptosin is a Novel Pro-Apoptotic Protein and Mediates Cell Death in Neurodegeneration 

      Zhang, Han; Zhang, Yun-wu; Chen, Yaomin; Huang, Xiumei; Zhou, Fangfang; Wang, Weiwei; Xian, Bo; Zhang, Xian; Masliah, Eliezer; Chen, Quan; Han, Jing-Dong J.; Bu, Guojun; Reed, John C.; Liao, Francesca (2012-10-31)
      Apoptosis is an essential cellular process in multiple diseases and a major pathway for neuronal death in neurodegeneration. The detailed signaling events/pathways leading to apoptosis, especially in neurons, require further ...