Browsing 生物医学-已发表论文 by Author "Andersen, B"
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LMO4 can interact with Smad proteins and modulate transforming growth factor-beta signaling in epithelial cells
Lu, Z; Lam, KS; Wang, N; Xu, X; Cortes, M; Andersen, B; 吕忠显 (2006)LIM- only protein 4 ( LMO4) plays critical roles in mammalian development, and has been proposed to play roles in epithelial oncogenesis, including breast cancer. As LMO4 is highly expressed in the epithelial compartments ... -
The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells
Wang, N; Lin, KK; Lu, Z; Lam, KS; Newton, R; Xu, X; Yu, Z; Gill, GN; Andersen, B; 吕忠显 (2007)The nuclear LIM-only protein 4 (LMO4) is upregulated in breast cancer, especially estrogen receptor-negative tumors, and its overexpression in mice leads to hyperplasia and tumor formation. Here, we show that deletion of ...