Effect of benzo(a)pyrene and pyrene exposure on hepatic superoxide dismutase in Mugil so-iuy
- 环境生态－已发表论文 
在实验生态条件下 ,浓度范围 0 .1～ 5 0 μg/L的苯并 (a)芘和芘的短期暴露 (7d) ,5 0 μg/L浓度组造成梭鱼肝脏SOD活性先抑制后诱导的效应 ;5 μg/L浓度在 7d的暴露中 ,SOD活性未出现诱导而是抑制 ;同样在 5 0μg/L浓度下 ,苯并 (a)芘暴露 4d后SOD活性出现诱导 ,而芘在暴露 7d后才出现诱导 ,这间接反映了苯并 (a)芘和芘的毒性大小。这些结果说明梭鱼肝脏SOD活性与苯并 (a)芘和芘暴露有一定的相关性 ,可以作为海洋环境多环芳烃污染监测的一种生物标志物。The effects of benzo(a)pyrene and pyrene exposure in a short period of time (7 days) on hepatic Superoxide dismutase (SOD) activity in Mugil so-iuy were studied at concentration of 0.1～50 μg/L,in experimental condition.The results showed that the SOD activities were inhibited at first and then induced in the fishes exposed to concentration of 50 μg/L.The SOD activity was induced in the fishes exposed to BaP at concentration of 50 μg/L for 4 days,while induced in the fishes exposed to pyrene at same concentration for 7 days. This indicated indirectly the toxicities of BaP and pyrene. These results suggested that the hepatic SOD activity in Mugil so iuy have quite retativity to BaP or pyrene exposure,the SOD activity could be one of the biomarkers applied to monitoring marine PAHs contamination.