Micro-extraction Determinationof Alkylphenolic Acids in Chinese Patent Medicine GBE with n-hexane Extract by LiquidChromatography - mass Spectrometry
- 海洋环境－已发表论文 
正己烷萃取,并用HPLC-UV、HPLC-MS对中成药银杏浸膏(GBE)中微量烷基酚酸进行定性、定量分析。正己烷萃取效率高、共萃杂质少。在优化的实验条件下,平均回收率为98.9%(n=5)。银杏烷基酚酸(M=346)的HPLC-UV检测限为0.1μg/g,线性范围为0.5～10μg/g。With n-hexane extraction, the qualitative and quantitative analyses of alkylphenolic acids in Chinese patent medicineGBE (Ginkgo Bilobu Extract) were carried out with liquid chromatography-UV detector and mass spectrometry detector. Then-hexane was proven to be a very efficient extracting reagent, and few interfering materials were coextracted. Under the optimizedexperimental conditions, the recovery was 98.9%(n=5), the detection limit was 0.1μg/g, and the linear range was between 0.5～10μg/g for Ginkgo Biloba alkylphenolic acid of molecular weight of 346.