Research progress in PAHs degradation genes and enzymes
- 生命科学－已发表论文 
[中文文摘]由于环境中的多环芳烃(PAHs)具有高遗传毒性和“三致”性(致癌、致畸和致突变),其生物降解基因和降解功能酶研究备受关注。多环芳烃双加氧酶是近年来研究较多的多环芳烃降解的关键酶系之一,主要由细菌产生,可通过氧化反应使多环芳烃开环生成小分子的中间产物并最终氧化成CO2和水。目前,有关这类酶的理化性质、结构特点、功能等的研究相继开展,本文对PAHs降解基因、降解酶的研究现状与发展趋势进行综述。[英文文摘] Polycyclic aromatic hydrocarbons (PAHs) are a group of organic pollutants that accumulated in the environment due to a variety of anthropogenic activities. More and more attention has been paid to PAHs, because of their toxic, carcinogenic and mutagenic potential. The aromatic ring-cleaving enzymes produced by microbes play a definitive role in the metabolism of aromatic compounds. These enzymes can catalyze the addition of two atoms of molecular oxygen directly onto aromatic rings and their derivatives, with subsequent cleavage of aromatic rings. At present, the studies on the physical and chemical properties, molecular structure, and functions of these enzymes are carried on, and this paper reviewed the current status and trend on the research of the genes and enzymes involved in PAHs degradation.