The Development and Assessment of the Quality of Life Instrument for Hepatitis B Patients
目的:编制适合我国乙型肝炎患者的生存质量测定量表(QOL-HBV)。方法:对134名患者进行测量,考察QOL-HBV量表各条目的鉴别度、结构效度、内容效度、效标效度和信度。结果:量表的30个条目均具有鉴别度。因子分析提取的8个因子可以归纳为为社会适应、心理、生理3个维度。验证性因子分析χ2/DF为1.310,GFI为0.972,AGFI为0.967;量表和3个维度的Cronbachα系数分别为0.9353、0.863、0.868、0.835。QOL-HBV量表的各维度与SF-36量表对应的维度除精神健康、活力维度外均具有相关性(P<0.05),且相关系数大都大于0.4。结论:QOL-HBV具有较好的信度、效度,可以作为我国乙型肝炎患者生存质量简捷的测量工具。Objective: To develop a quality of life instrument for hepatitis B patients(QOL-HBV) and examine it's reliability and validity.Methods:The item analysis, construct validity, content validity, criteria validity, reliability and discriminate were assessed by a survey on 134 HBV patients with QOL-HBV.Results:Item analysis showed that QOL-HBV had satisfactory item discrimination. Eight common factors were extracted by exploratory factor analysis and they can be reduced to three domains. The χ2/DF was 1.310, GFI was 0.972 and AGFI was 0.967 by the confirmatory factor analysis. The coefficients of Cronbach's α of the instrument and all domains were above 0.80. In comparison with SF-36, there was good correlation among corresponding domains.Conclusion:QOL-HBV is a good scale in testing the quality of life, which has good reliability and validity.