Inflammation,Promoting Cancer or Protecting the Body Against Cancer?
[中文文摘]任何事物都具有两面性,炎症反应也不例外。作为生物体内最常见的生理反应之一,炎症反应不仅可以消除细菌、病毒等外界因素的入侵,还是免疫系统用于清除病变细胞的工具,从而保证机体健康;另一方面,炎症可以促进肿瘤的发展、转移和恶变。解析炎症反应和癌症的关系,了解其中的分子机制,有助于发展新的预防和治疗癌症的方法。[英文文摘]Inflammation is a double-edged sword in tumorigenesis and tumor development. While it plays an important role in promoting cancer, inflammation is a major defense mechanism of the immune system in protecting the body against cancer as well as infection. The relationship between inflammation and tumor in different stages of cancer development is a key issue in cancer study. The aim of our 973 project is to gain a better understand of the role of inflammatory signaling pathways and thereby provides new ideas ...for preventing and treating cancers.