Now showing items 1-5 of 5
The Silencing of Pokemon Attenuates the Proliferation of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Inhibiting the PI3K/Akt Pathway
(PLOS ONE, 2012-12-26)
Pokemon (POK erythroid myeloid ontogenic factor), which belongs to the POK protein family, is also called LRF, OCZF and FBI-1. As a transcriptional repressor, Pokemon assumes a critical function in cellular differentiation ...
Silencing of Pokemon Enhances Caspase-Dependent Apoptosis via Fas- and Mitochondria-Mediated Pathways in Hepatocellular Carcinoma Cells
(PUBLIC LIBRARY SCIENCE, 2013-Jul 1)
The role of Pokemon (POK erythroid myeloid ontogenic actor), a recently identified POK transcription factor with proto-oncogenic activity, in hepatocellular carcinogenesis has only been assessed by a few studies. Our ...
Pyruvate Kinase M2 Plays a Dual Role on Regulation of the EGF/EGFR Signaling via E-Cadherin-Dependent Manner in Gastric Cancer Cells
(PUBLIC LIBRARY SCIENCE, 2013-Jun 2)
Background and Aims: EGFR activation and PKM2 expression are instrumental in tumorigenesis. EGFR activation regulates PKM2 functions in a subcellular compartment-dependent manner and promotes gene transcription and tumor ...
miRNA423-5p regulates cell proliferation and invasion by targeting trefoil factor 1 in gastric cancer cells
(ELSEVIER IRELAND LTD, 2014-05-28)
TFF1 is a small, secreted protein in the TFF family that has a pivotal role as a motogenic factor in epithelial restitution and cell motility, and as a tumor suppressor gene in the stomach. In this study, we identified ...
Piezo1 Is as a Novel Trefoil Factor Family 1 Binding Protein that Promotes Gastric Cancer Cell Mobility In Vitro
(SPRINGER, 2014 JUL)
Trefoil factor family 1 (TFF1) is a member of the TFF-domain peptide family involved in epithelial restitution and cell motility. Recently, we screened Piezo1 as a candidate TFF1-binding protein. We aimed to confirm Piezo1 ...