Now showing items 1-6 of 6
Anti-Angiogenic and Anti-Inflammatory Effects of SERPINA3K on Corneal Injury
(PLOS ONE, 2011-01-31)
SERPINA3K is a member of the serine proteinase inhibitor ( SERPIN) family. Here we evaluated the therapeutic effects of SERPINA3K on neovascularization and inflammation in a rat cornea alkali burn model that is commonly ...
Truncated ErbB2 Expressed in Tumor Cell Nuclei Contributes to Acquired Therapeutic Resistance to ErbB2 Kinase Inhibitors
(MOL CANCER THER, 2011-08)
ErbB2 tyrosine kinase inhibitors (TKI) block tyrosine autophosphorylation and activation of the full-length transmembrane ErbB2 receptor (p185 ErbB2). In addition to p185 ErbB2, truncated forms of ErbB2 exist in breast ...
Oxygen Tension Affects Terminal Differentiation of Corneal Limbal Epithelial Cells
(J CELL PHYSIOL, 2011-09)
Oxygen concentration has been shown to be crucial in the proliferation and differentiation of various types of cells, while the impact of oxygen tension on the lineage commitment of epithelial cells remains elusive. In ...
Modulation of the canonical Wnt pathway by Benzalkonium Chloride in corneal epithelium
(EXP EYE RES, 2011-10)
Benzalkonium Chloride (BAC) is commonly used in eyedrops. Although the cytotoxicity of BAC has been reported, the mechanism underlying its toxic effect has not been elucidated. The present study investigated the role of ...
Amniotic membrane inhibits squamous metaplasia of human conjunctival epithelium
(AM J PHYSIOL-CELL PH, 2011-07)
Tan Y, Qiu F, Qu Y, Li C, Shao Y, Xiao Q, Liu Z, Li W. Amniotic membrane inhibits squamous metaplasia of human conjunctival epithelium. Am J Physiol Cell Physiol 301: C115-C125, 2011. First published March 16, 2011; ...
Corneal Alternations Induced by Topical Application of Benzalkonium Chloride in Rabbit
(PLOS ONE, 2011-10-12)
Benzalkonium chloride (BAC) is the most common preservative in ophthalmic preparations. Here, we investigated the corneal alternations in rabbits following exposure to BAC. Twenty-four adult male New Zealand albino rabbits ...