Now showing items 1-10 of 206
A Mouse Model of Limbal Stem Cell Deficiency Induced by Topical Medication With the Preservative Benzalkonium Chloride
(ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013-09-24)
Purpose. To develop a mouse model of limbal stem cell deficiency (LSCD) by topical administration of benzalkonium chloride (BAC). Methods. BAC solutions (0%–0.5%) were applied to the mouse ocular surface for 4 weeks. ...
Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb
The Mediator is a multi-subunit complex that transduces regulatory information from transcription regulators to the RNA polymerase II apparatus. Growing evidence suggests that Mediator plays roles in multiple stages of ...
Toxicity of superparamagnetic iron oxide nanoparticles: Research strategies and implications for nanomedicine
(IOP PUBLISHING LTD, 2013)
Superparamagnetic iron oxide nanoparticles (SPIONs) are one of the most versatile and safe nanoparticles in a wide variety of biomedical applications. In the past decades, considerable efforts have been made to investigate ...
Metabolomic Profilings of Urine and Serum from High Fat-Fed Rats via H-1 NMR Spectroscopy and Pattern Recognition
(HUMANA PRESS INC, 2013)
H-1 NMR spectroscopy in combination with multivariate statistical analysis was applied to explore the metabolic variability in urine and serum of high fat-fed rats relative to normal chow-fed ones. Metabolites contributing ...
Risk factors for No 12p and No 12b lymph node metastases in advanced gastric cancer in China
(INFORMA HEALTHCARE, 2013)
Background. The risk factors for No. 12p and No. 12b lymph node (LN) metastases in advanced gastric cancer (GC) remain controversial. The aim of this study was to investigate the risk factors for No. 12p and No. 12b LN ...
Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma
(ELSEVIER SCIENCE INC, 2013)
Overexpression of the cellular nuclear exportin 1, more commonly called chromosomal region maintenance 1 (CRM1), has been associated with malignant progression and mortality. Therefore, activation of nuclear export can ...
Hepatectomy in Elderly Patients: Does Age Matter?
With the increase in average life expectancy in recent decades, the proportion of elderly patients requiring liver surgery is rising. The aim of the meta-analysis reported here was to evaluate the safety and efficacy of ...
Chloride intracellular channel 1 is overexpression in hepatic tumor and correlates with a poor prognosis
Chloride intracellular channel 1 (CLIC1) is expressed in many human tissues and has been reported to be involved in the regulation of cell cycle, cell proliferation, and differentiation. Its roles in human hepatic tumor, ...
Adult intussusception with perforation caused by hemangioma in the distal ileum
(ELSEVIER TAIWAN, 2013)