Now showing items 1-3 of 3
SERPINA3K Protects against Oxidative Stress via Modulating ROS Generation/Degradation and KEAP1-NRF2 Pathway in the Corneal Epithelium
(ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2012-07)
PURPOSE. We recently reported that SERPINA3K (SA3K), a member of the serine proteinase inhibitor (SERPIN) family, has antiangiogenic and anti-inflammatory activities. Here we investigated the antioxidant effects of SA3K ...
Modulation of the canonical Wnt pathway by Benzalkonium Chloride in corneal epithelium
(EXP EYE RES, 2011-10)
Benzalkonium Chloride (BAC) is commonly used in eyedrops. Although the cytotoxicity of BAC has been reported, the mechanism underlying its toxic effect has not been elucidated. The present study investigated the role of ...
Regulation of Endothelial Progenitor Cell Release by Wnt Signaling in Bone Marrow
(ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013)
PURPOSE. Endothelial progenitor cells (EPC) have been shown to participate in ischemia-induced retinal neovascularization (NV). Overactivation of Wnt signaling has a pathogenic role in ischemia-induced retinal NV. The ...