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The toxicological study of CCNU controlled release film in vivo
We planted the Lomustine (CCNU) controlled release films into normal mice, and after a period of time observed the effects of the films on the blood cells and the brain nerve cells of the mice. Compared with the traditional ...
Improved controlled release study of lomustine
Lomustine(CCNU) microcapsules was prepared by improved recoacervation method, then mixed microcapsules with 0.7% collagen smelling solution to prepare the emulsion, spreaded the emulsion aln the plate to form membrane and ...
Assay of CCNU in tumor by RP-HPLC
This paper reports a RP-HPLC method for the determination of Lomustine (CCNU) in mouse tumor tissue. CCNU was separated and determined on a reverse-phase C-18 5 mu m column with a mobile phase of H2O-acetonitrile (54:46), ...