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Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution
(2011-10-25)
Both folic acid (FA)- and methoxypoly(ethylene glycol) (mPEG)- conjugated chitosan nanoparticles (NPs) had been designed for targeted and prolong anticancer drug delivery system. The chitosan NPs were prepared with combination ...
Surface modification of Mitoxantrone-loaded PLGA nanospheres with chitosan
(2009-10-15)
The purpose of this research was to develop polylactic-co-glycolic acid (PLGA) nanospheres surface modified with chitosan (CS). Mitoxantrone- (MTO-) loaded PLGA nanospheres were prepared by a solvent evaporation technique. ...
Cytotoxic effects and the mechanism of three types of magnetic nanoparticles on human hepatoma BEL-7402 cells
(2011-07-29)
The evaluation of the toxicity of magnetic nanoparticles (MNPs) has attracted much attention in recent years. The current study aimed to investigate the cytotoxic effects of Fe(3)O(4), oleic acid-coated Fe(3)O(4) (OA-Fe(3)O(4)), ...