Now showing items 1-11 of 11

    • A Monoclonal Antibody Against the Catalytic Domain of PTP1B 

      Zeng, Fanwei; Ni, Erru; Wang, Shengyu; Lv, Sha; Cao, Chang; Zhang, Haipeng; Lv, Haiyan; Chen, Xiaoli; Yan, Jianghua; Luo, Fanghong; 罗芳洪 (MARY ANN LIEBERT INC, 2012-06)
      Protein tyrosine phosphatase 1B (PTP1B), a member of the protein tyrosine phosphatase (PTP) family, plays a crucial role in metabolic signaling, with insulin and leptin signaling being well studied. New evidence indicates ...
    • A monoclonal antibody targeting neuropilin-1 inhibits adhesion of MCF7 breast cancer cells to fibronectin by suppressing the FAK/p130cas signaling pathway 

      Zeng, Fanwei; Luo, Fanghong; Lv, Sha; Zhang, Haipeng; Cao, Chang; Chen, Xiaoli; Wang, Shengyu; Li, Zhe; Wang, Xianjiang; Dou, Xiaofeng; Dai, Yujuan; He, Mingjun; Zhang, Yafei; Lv, Haiyan; Yan, Jianghua; Chen, Yuqiang; 罗芳洪; 陈晓莉; 颜江华; 陈玉强 (LIPPINCOTT WILLIAMS & WILKINS, 2014 JUL)
      Neuropilin-1 (NRP-1) is a nontyrosine kinase coreceptor for semaphorin 3A and the vascular endothelial growth factor involved in tumor angiogenesis, growth, and metastasis and is regarded as a promising target for cancer ...
    • A Suppressor of Cytokine Signaling 1 Antagonist Enhances Antigen-Presenting Capacity and Tumor Cell Antigen-Specific Cytotoxic T Lymphocyte Responses by Human Monocyte-Derived Dendritic Cells 

      Wang, Yongjun; Wang, Shengyu; Ding, Yuan; Ye, Yanhua; Xu, Yingyi; He, Huixiang; Li, Qiaozhen; Mi, Yanjun; Guo, Chunhua; Lin, Zhicai; Liu, Tao; Zhang, Yaya; Chen, Yuqiang; Yan, Jianghua; 陈玉强; 颜江华 (AMER SOC MICROBIOLOGY, 2013)
      The suppressor of cytokine signaling 1 (SOCS1) has emerged as a critical inhibitory molecule for controlling the cytokine response and antigen presentation by dendritic cells (DCs), thereby regulating the magnitude of both ...
    • Adiponectin induces growth inhibition and apoptosis in cervical cancer HeLa cells 

      Xie, Lianying; Wang, Yongjun; Wang, Shengyu; Wu, Na; Chen, Yuqiang; Yan, Jianghua; 颜江华 (2011-08)
      Obesity is a known risk factor for postmenopausal cervical cancer. In human, plasma adiponectin (ADPN) levels are inversely associated with obesity. ADPN may influence the pathogenesis of cervical cancer. In this paper, ...
    • Current situation and future development of medical tourism in China 

      Yan, Ruorong; Yan, Jianghua; Sun, L; Lin, B; 颜江华 (2007)
      Medical Tourism is a rising-sun industry, which could create happiness and healthy at the same time. The Medical Tourism in China is a burgeoning industry. In this paper, the current situation, advantages and problems of ...
    • Inhibitory Effect of Neuropilin-1 Monoclonal Antibody (NRP-1 MAb) on Glioma Tumor in Mice 

      Chen, Lukui; Miao, Wei; Tang, Xiaoyong; Zhang, Haipeng; Wang, Shengyu; Luo, Fanghong; Yan, Jianghua; 陈陆馗; 罗芳洪; 颜江华 (AMER SCIENTIFIC PUBLISHERS, 2013)
      This article reports the effect of Neuropilin-1 monoclonal antibody (NRP-1 MAb) on glioma cell lines in vitro and the effect on nude mice bearing glioma tumor (U87) in vivo. MTT, the scratch test and transwell test were ...
    • Metformin interacts with AMPK through binding to gamma subunit 

      Zhang, Yaya; Wang, Yongjun; Bao, Chuanen; Xu, Yingyi; Shen, Huili; Chen, Junjie; Yan, Jianghua; Chen, Yuqiang; 陈玉强 (SPRINGER, 2012-09)
      A series of novel fluoropolymer anion exchange membranes based on the copolymer of vinylbenzyl chloride, butyl methacrylate, and hexafluorobutyl methacrylate has been prepared. Fourier transform infrared (FT-IR) spectroscopy ...
    • Monoclonal Antibody Against NRP-1 b1b2 

      Li, Xiang; Luo, Fanghong; Wang, Shengyu; Ni, Erru; Tang, Xiaoyong; Lv, Haiyan; Chen, Xiaoli; Chen, Lukui; Yan, Jianghua; 颜江华 (2011-08)
      Neuropilin-1 is a member of the neuropilins family protein, which contains a large extracellular domain (a1a2, b1b2 and c), a single transmembrane domain, and a short cytoplasmic tail. NRP-1 plays a critical role in ...
    • Novel superparamagnetic iron oxide nanoparticles for tumor embolization application: Preparation, characterization and double targeting 

      Chen, Xiaoli; 陈晓莉; Lv, Haiyan; Ye, Min; Wang, Shengyu; Ni, Erru; Zeng, Fanwei; Cao, Chang; Luo, Fanghong; Yan, Jianghua (ELSEVIER SCIENCE BV, 2012-04-15)
      The goal of this study was to develop novel embolic nanoparticles for targeted tumor therapy with dual targeting: magnetic field-guided and peptide-directed targeting. The embolic nanoparticles SP5.2/tTF-OCMCs-SPIO-NPs ...
    • Recombinant human leptin induces growth inhibition and apoptosis in human gastric cancer MGC-803 cells 

      Wu, Na; Wang, Yongjun; Wang, Shengyu; Chen, Yuqiang; Yan, Jianghua; 陈玉强; 颜江华 (SPRINGER-VERLAG ITALIA SRL, 2013)
      The aim of this study is to investigate the effect of recombinant human leptin (rhLep) on the proliferation of human gastric cancer MGC-803 cells and its underlying mechanisms. RT-PCR was performed to identify the expression ...
    • The Expression and Significance of Neuropilin-1 (NRP-1) on Glioma Cell Lines and Glioma Tissues 

      Chen, Lukui; Miao, Wei; Tang, Xiaoyong; Zhang, Haipeng; Wang, Shengyu; Luo, Fanghong; Yan, Jianghua; 陈陆馗; 罗芳洪; 颜江华 (AMER SCIENTIFIC PUBLISHERS, 2013)
      We detected the expressions of neuropilin-1 (NRP-1) on glioma cell lines and glioma tissues by neuropilin-1 monoclonal antibody (NRP-1 MAb). The expressions of NRP-1 on glioma cell lines and glioma tissues were detected ...