Now showing items 1-5 of 5

    • Anti-Angiogenic and Anti-Inflammatory Effects of SERPINA3K on Corneal Injury 

      Liu, Xiaochen; Lin, Zhirong; Zhou, Tong; Zong, Ronrong; He, Hui; Liu, Zhen; Ma, Jian-xing; Liu, Zuguo; Zhou, Yueping; 刘祖国; 周跃平 (PLOS ONE, 2011-01-31)
      SERPINA3K is a member of the serine proteinase inhibitor ( SERPIN) family. Here we evaluated the therapeutic effects of SERPINA3K on neovascularization and inflammation in a rat cornea alkali burn model that is commonly ...
    • Antiangiogenic and Antineuroinflammatory Effects of Kallistatin Through Interactions With the Canonical Wnt Pathway 

      Liu, Xiaochen; Zhang, Bin; McBride, Jeffrey D.; Zhou, Kevin; Lee, Kyungwon; Zhou, Yueping; Liu, Zuguo; Ma, Jian-xing; 周跃平; 刘祖国 (AMER DIABETES ASSOC, 2013)
      Kallistatin is a member of the serine proteinase inhibitor superfamily. Kallistatin levels have been shown to be decreased in the vitreous while increased in the circulation of patients with diabetic retinopathy (DR). ...
    • Modulation of the canonical Wnt pathway by Benzalkonium Chloride in corneal epithelium 

      Zhou, Yueping; Liu, Qiuping; Zhou, Tong; Lin, Zhirong; Zong, Rongrong; Liu, Zhen; Sun, Feng; Shao, Yi; Liu, Xiaochen; Ma, Jian-xing; Liu, Zuguo; 周跃平; 刘祖国 (EXP EYE RES, 2011-10)
      Benzalkonium Chloride (BAC) is commonly used in eyedrops. Although the cytotoxicity of BAC has been reported, the mechanism underlying its toxic effect has not been elucidated. The present study investigated the role of ...
    • Regulation of Endothelial Progenitor Cell Release by Wnt Signaling in Bone Marrow 

      Liu, Xiaochen; McBride, Jeffrey; Zhou, Yueping; Liu, Zuguo; Ma, Jian-xing; 周跃平; 刘祖国 (ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013)
      PURPOSE. Endothelial progenitor cells (EPC) have been shown to participate in ischemia-induced retinal neovascularization (NV). Overactivation of Wnt signaling has a pathogenic role in ischemia-induced retinal NV. The ...
    • SERPINA3K Protects against Oxidative Stress via Modulating ROS Generation/Degradation and KEAP1-NRF2 Pathway in the Corneal Epithelium 

      Zhou, Tong; Zong, Rongrong; Zhang, Zhoujing; Zhu, Chengpeng; Pan, Fangyu; Xiao, Xinye; Liu, Zhen; He, Hui; Ma, Jian-xing; Liu, Zuguo; Zhou, Yueping; 周跃平; 周彤; 马建兴; 刘祖国 (ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2012-07)
      PURPOSE. We recently reported that SERPINA3K (SA3K), a member of the serine proteinase inhibitor (SERPIN) family, has antiangiogenic and anti-inflammatory activities. Here we investigated the antioxidant effects of SA3K ...